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Epigenetics: Experience Writes on the Genome

Conrad Waddington / Michael Meaney · 1942

"Epigenetics shows experience can leave chemical marks on DNA that change gene expression without changing the code — and some marks, via careful animal models, appear responsive to stress, nutrition, and care."

The idea

Waddington coined 'epigenetics' in 1942 for how the same genome produces different outcomes by context. Meaney showed in the 2000s that rat pups licked more by mothers grew different stress responses because of a chemical mark, not a different gene.

Why it works
The takeaway — recall it first
Further reading

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